Clair Crewe, PhD
Assistant Professor, Cell Biology & Physiology
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The Crewe lab uses transgenic mouse lines, cell culture and biochemistry to understand extracellular vesicle (EV)-mediated signaling during homeostatic and pathologic metabolic regulation. We are focused on understanding this in the context of obesity and type 2 diabetes with a particular emphasis on adipocyte-derived EVs. We are particularly excited about a subpopulation of EVs from adipocytes carry damaged mitochondria which are transferred to other organs.
Research keywords: extracellular vesicles; metabolism; Obesity
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