We investigate adaptations for intracellular parasitism, focusing on the protozoan parasites Toxoplasma gondii and Cryptosporidium parvum. We currently employ a variety of genetic, biochemical and cellular approaches to address important biological questions. Our studies have revealed the importance innate immunity mechanisms in controlling infection and in parasite virulence factors that thwart innate defenses. We also have several translational projects aims at developing small molecule inhibitors to treat infect and these studies involve high throughput screening, structural biology. and medicinal chemistry.
Research keywords: microbiology; molecular biology; pathogenesis
Basic information
| Pronouns: | He/Him/His |
| Mentoring statement: | Not provided. |
| Some former postdocs’ career outcomes: | Our work has been continuously funded by the National Institutes of Health as well as several Foundations for the past 30 years. During my time at Washington University, I have mentored 20 Ph.D. thesis students in my lab and more than 45 postdoctoral fellows. Former trainees in my lab have held fellowships from National Science Foundation, National Institutes of Health, American Heart Association, and other international science organizations and many of these individuals have gone on to direct labs at major Universities in the USA and abroad, to hold administrative positions in science policy, or to become leaders in industry. |
Postdoc openings within the next year
| Number of postdoc positions: | 2 |
| Postdoc eligibility: | U.S. Citizens or Permanent Residents Current Visa-Holding Trainees in the U.S. International Trainees Outside the U.S. |