Historically, reactive astrocytes and neuroinflammation were thought to arise secondary to neuronal cell death in neurodegenerative diseases with little relevance. However, astrocytes and neuroinflammation are beginning to emerge as critical targets of neurological disorders once thought to afflict neurons selectively. We aim to understand the molecular mechanisms that regulate reactive astrocytes and their neurotoxicity in neurodegenerative diseases, including Alzheimer’s disease. To investigate these mechanisms, we combine biochemistry, molecular biology, cellular models of inflammation and mouse models of neurodegenerative diseases. We are also interested in developing novel therapies targeting these pathways to reduce neuroinflammation for potential therapeutic intervention.
Research keywords: astrocytes; immunotherapies; Alzheimer’s disease
Basic information
| Pronouns: | He/Him/His |
| Mentoring statement: | Not provided. |
| Some former postdocs’ career outcomes: | Currently, we have two postdocs that joined in 2020 and 2022. |
Postdoc openings within the next year
| Number of postdoc positions: | 2 |
| Postdoc eligibility: | U.S. Citizens or Permanent Residents Current Visa-Holding Trainees in the U.S. International Trainees Outside the U.S. |