Nupam Mahajan, PhD

Endowed Professor, Surgery

The lab theme is to determine how tyrosine kinases, phosphatases, demethylases and nuclear receptors regulates epigenetic processes that affect cellular homeostasis, immune impairment and cancer cell survival. Current Projects in Lab Epigenetic signaling in dampening immune response to tumors Characterization of new subsets of T cells and neutrophils Androgen regulated immune response Characterization of KDM6 inhibitors New `dual’ therapeutic molecules Major findings of our lab include: Discovered 5 new epigenetic events: Identified a novel lncRNA, NXTAR Developed inhibitor for ACK1, (R)-9b Identified AKT Tyr176-phosphorylation Identified AR Lys609-acetylation Identified a new class of KDM6 inhibitor

Research keywords: Breast & Prostate Cancer; Immune regulation; Epigenetics

Basic information

Mentoring statement:Not provided.
Some former postdocs’ career outcomes:Two of our postdocs started their own labs.

Postdoc openings within the next year

Number of postdoc positions:2
Postdoc eligibility:U.S. Citizens or Permanent Residents
Current Visa-Holding Trainees in the U.S.
International Trainees Outside the U.S.