We are intrigued with the conundrum that while DNA replication and repair are essential for viability, cancer cells with defects in these pathways evolve mechanisms to ensure rapid proliferation. Unravelling this mystery offers possibilities to understand mechanisms that lead to genomic instability and identify vulnerabilities that can catalyze the development of improved therapeutic regimens. Ongoing projects in the lab includes: • Improve chemotherapeutic responses in BRCA-mutant cancers • Elucidate the etiology of oncogene-high ovarian cancers • Deciphering the mechanistic basis of mutational signatures in cancer genomes Key approaches: Several functional genomic approaches including CRISPR genetic screens and cell biology
Research keywords: DNA repair and replication; Ovarian and Breast Cancer; Oncogene and Tumor Suppressor
Basic information
| Pronouns: | She/Her/Hers |
| Mentoring statement: | Find it here. |
| Some former postdocs’ career outcomes: | Not provided. |
Postdoc openings within the next year
| Number of postdoc positions: | 2 |
| Postdoc eligibility: | U.S. Citizens or Permanent Residents Current Visa-Holding Trainees in the U.S. International Trainees Outside the U.S. |