Biomedical Engineering

Our mission is to develop innovative techniques for improving the lives of patients with brain diseases. Our team is currently working on developing the following techniques: ultrasound-mediated brain drug delivery techniques for the treatment of brain cancer, ultrasound-enabled brain tumor biomarker release techniques for the diagnosis of brain cancer, and ultrasound neuromodulation techniques for understanding brain functions.

Research keywords: Neuroengineering; Brain cancer; Neuroscience

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Abhinav K. Jha's research is in the design, evaluation and translation of computational medical imaging methods for optimized performance in diagnostic and therapeutic tasks using quantitative measures of task performance. For this purpose, his group develops novel physics and artificial intelligence (AI)-based methods for image reconstruction, image enhancement, image analysis and task-based image-quality evaluation. One major research direction is in integrating AI and task-based assessment to make medical imaging more comfortable and accessible for patients by reducing acquisition dose and scanning times, and more valuable for physicians by automating image-analysis procedures and providing imaging biomarkers to monitor disease response. This research direction also includes studying the clinical deployment and ethical aspects of AI algorithms. Another major direction of research is developing low-count quantitative imaging methods for personalizing emerging cancer treatments. Towards this goal, his group develops statistical signal-processing approaches that maximize the extracted task-specific information from data measured by imaging systems.

Research keywords: Computational medical imaging; Artificial intelligence; Imaging Science

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TIRs is reaching out to prospective graduate students in Chemistry, Biochemistry and Neurosciences. This T32 training program provides a unique opportunity for recently graduated students interested in transitioning their careers into applied molecular imaging focused on design, preclinical validation, development, and translation of PET molecular imaging agents for diagnostic clinical nuclear medicine for application in neurodegenerative diseases (ADRDs).

Research keywords: PET; Probe-Development; Translational-Imaging

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