Emergency Medicine

The Mudd lab explores the T cell response to viral respiratory pathogens in living human subjects focusing on difficult to sample tissue compartments such as the draining lymph node, the lung mucosa and the nasopharyngeal mucosa. Using cutting edge tools such as single-cell RNA sequencing, paired V(D)J sequencing, TCR cloning and ex vivo human T cell line characterization, we explore the antigen-specific T cell response to these pathogens in our unique human cohorts following vaccination or natural infection.

Research keywords: T cell immunology; human immunology; influenza

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