Wayne Barnes, PhD

Associate Professor, Biochemistry & Molecular Biophysics

The Mayo Clinic has published a DNA 20mer (selected in vitro to bind myelin) that apparently leads to remyelinization and recovery in a mouse M.S. model. But it only works as a complex with 4 streptavidins, I.P. 3x per week, and is expected to be immunogenic. I have selected [SELEX] non-immunogenic 95mer nucleic acids that reach the brain from intravenous tail vein injections. These could replace the streptavidins, and were selected to carry a cargo of 45mer. Only 4h timepoint so far. Exciting idea for long lifetime.

Research keywords: multiple sclerosis; aptamers; DNA technology

Basic information

Mentoring statement:Not provided.
Some former postdocs’ career outcomes:Not provided.

Postdoc openings within the next year

Number of postdoc positions:1
Postdoc eligibility:U.S. Citizens or Permanent Residents
Current Visa-Holding Trainees in the U.S.