Our laboratory focuses on examining pathogenic events responsible for initiating the development of tissue-specific autoimmune diseases. We aim to dissect key factors involved in type 1 diabetes, an autoimmune disorder that destroys insulin-producing β-cells in the pancreatic islets. The research projects center on 1) Identifying antigenic targets involved in disease pathogenesis using immunopeptidomics to isolate and identify peptide epitopes presented by autoimmune-predisposing MHC molecules; 2) Studying the key features of antigen-specific T cells using single-cell transcriptomics and epigenetic approaches in mice and humans; 3) Examining tissue-resident macrophages that play a critical role in shaping the incoming autoimmune responses.
Research keywords: Autoimmunity; Antigen discovery and presentation; Antigen-specific T cells and tissue-resident macrophages
Basic information
| Pronouns: | He/Him/His |
| Mentoring statement: | Find it here. |
| Some former postdocs’ career outcomes: | Not provided. |
Postdoc openings within the next year
| Number of postdoc positions: | 2 |
| Postdoc eligibility: | U.S. Citizens or Permanent Residents Current Visa-Holding Trainees in the U.S. International Trainees Outside the U.S. |